beta-Thalassemia

A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.

Also Known As:

Cooley's Anemia; Thalassemia Major; Erythroblastic Anemia; Mediterranean Anemia; Thalassemia Minor; Microcytemia, beta Type; Thalassemia Intermedia; Thalassemia Major (beta-Thalassemia Major); Thalassemia Minor (beta-Thalassemia Minor); Thalassemia, beta Type; beta Thalassemia; Anemia, Cooley; Anemia, Cooleys; Anemias, Erythroblastic; Anemias, Mediterranean; Disease, Hemoglobin F; Intermedia, Thalassemia; Intermedias, Thalassemia; Major, Thalassemia (beta-Thalassemia Major); Majors, Thalassemia (beta-Thalassemia Major); Mediterranean Anemias; Microcytemias, beta Type; Minor, Thalassemia (beta-Thalassemia Minor); Minors, Thalassemia (beta-Thalassemia Minor); Thalassemia Intermedias; Thalassemia Major (beta Thalassemia Major); Thalassemia Majors (beta-Thalassemia Major); Thalassemia Minor (beta Thalassemia Minor); Thalassemia Minors (beta-Thalassemia Minor); Thalassemia, beta; Thalassemias, beta; Thalassemias, beta Type; Type Microcytemia, beta; Type Microcytemias, beta; Type Thalassemia, beta; Type Thalassemias, beta; beta Thalassemias; beta Type Microcytemia; beta Type Microcytemias; beta Type Thalassemia; beta Type Thalassemias; Anemia, Cooley's; Anemia, Erythroblastic; Anemia, Mediterranean; Hemoglobin F Disease

Hemic and Lymphatic Diseases: 7
- Hematologic Diseases: 3445
  - Anemia: 39278
    - Hemolytic Anemia: 6775
      - Congenital Hemolytic Anemia: 292
        Thalassemia: 6287
        beta-Thalassemia: 5562
  - Hemoglobinopathies: 2039
    - Thalassemia: 6287
      - beta-Thalassemia: 5562
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 960
- Inborn Genetic Diseases: 12342
  - Hemoglobinopathies: 2039
    - Thalassemia: 6287
      - beta-Thalassemia: 5562
  - Congenital Hemolytic Anemia: 292
    - Thalassemia: 6287
      - beta-Thalassemia: 5562

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Drug/Important Bio-Agent (IBA)